Postdoctoral researcher in cellular neuroscience / cancer neuroscience

This project focuses on the interaction between neurons and glioblastoma cells in the brain and how this crosstalk contributes to tumor growth. We use patient-derived glioblastoma cell lines and human neurons generated from induced pluripotent stem cells (iPSC).

We have established a standardized and scalable in vitro model to study synaptic communication between neurons and tumor cells. This system has been validated using neuronal stimulation combined with live cell imaging and confocal microscopy to detect synaptic responses in tumor cells.

We are looking for an independent junior postdoctoral researcher who will further develop and exploit this model system.

You will:

• characterize synaptic communication between neurons and tumor cells in vitro in detail;
• develop and execute a CRISPR-based screening approach to identify key regulators of neuron–tumor synapses;
• identify potential therapeutic targets that may slow down glioblastoma progression;
• collaborate closely with a dedicated technician and a PhD candidate;
• contribute to experimental design, data interpretation and scientific publications.

You will work at the interface of cellular neuroscience, cancer biology and functional genomics, in a rapidly evolving research field with strong translational potential.

We are looking for a motivated scientist with a strong experimental and analytical background.

You bring:

• a PhD in cellular neuroscience, biophysics or a related field;
• extensive hands-on experience with in vitro models, preferably iPSC-based systems;
• strong expertise in live cell imaging and advanced microscopy techniques;
• experience with complex data analysis and bioinformatics approaches;
• a strong drive to build an academic research career in neuroscience.