Assistant professor or postdoc intestinal function and failure

Intestinal failure is most commonly defined as ‘’the reduction of gut function below the minimum necessary for the absorption of macronutrients and/or fluids and electrolytes, such that intravenous supplementation is required to maintain health and/or growth”. Despite its profound impact, the underlying causes of chronic intestinal failure in children remain poorly understood, and effective therapeutic options are limited.

• As an Assistant Professor, you will lead cutting-edge translational research with our Tytgat Institute-based research team into the causes of chronic intestinal failure in children, working closely with the clinical team at the pediatric department. You will conduct laboratory-based research at the Tytgat Institute, utilizing its state-of-the-art facilities, while fostering collaboration with clinical colleagues at the Emma Center for Personalized Medicine (Emma CPM) and the pediatric gastroenterology team at Kinderbuikcentrum Amsterdam UMC. This interdisciplinary approach will allow you to bridge the gap between scientific research and clinical care, identifying novel connections across various research projects.
• In addition to your research responsibilities, you will contribute to teaching by mentoring students and PhD candidates, and translating newly acquired scientific insights into educational resources and knowledge-sharing initiatives. You will also participate in the (Bio)medical curriculum, with teaching expected to constitute 10-20% of your time.
• We expect you to actively contribute to securing research funding and expanding your research team, furthering the impact of your work and the department’s goals.

This is an opportunity for an ambitious young scientist to take a next step in their academic career. You will be able to join forces with our current working groups at Tytgat Institute; bioinformatics, sequencing and (spatial) imaging core groups and Amsterdam UMC facilities. The ideal candidate will have a proven track record in leading scientific teams and securing research funding, or be a senior postdoctoral researcher demonstrating strong potential to develop these skills within the next 1-2 years. This is a unique opportunity to build your independent research career in a supportive, cutting-edge environment. At Amsterdam UMC, we are committed to your professional and personal growth, offering extensive opportunities for development, collaboration, and further training.

• You hold a PhD in Medicine, Medical Biology, Biochemistry, or a related field.
• You have proven experience in leading, and working with, various research teams.
• You have a strong background in molecular and cellular pathways involved in intestinal development and/or function, with a particular focus on groundbreaking molecular cell biology and genetics.
• Your research aims to uncover innovative therapies for children with chronic intestinal failure.
• As a creative and forward-thinking scientist, you generate hypotheses based on literature insights and input from collaborating clinicians, and design experiments to rigorously test these ideas.
• You demonstrate a track record of successful international collaboration and have the ability to secure competitive funding to expand your research program.
• You are adept at managing the progress and outputs of your team, as well as the financial aspects of multiple, parallel research projects.
• Fluency in both Dutch and English is essential, or a willingness to learn Dutch in the near future to integrate into our team and community.