Working at Amsterdam UMC

Project Manager Cell Therapy

We are looking for a robust project/program manager who is on all levels able to steer our team towards the in house manufacturing of our newly developed CAR-T Cell Therapies.
Project Manager Cell Therapy
Apply now
  • Hours: 32 36 uur per week
  • Location: Locatie VUmc
  • Contract type: fixed-term
  • Salary: € 5.659 - € 6.867
  • React until: 13 August 2022
Apply now Apply within 7 day(s)
The project

The research of the department focuses on improving treatment strategies for lymphoid hematological malignancies. In view of that, we are developing next generation optimized Chimeric Antigen Receptor (CAR)-T cells, with the aim to manufacture these in house and to evaluate the CAR T cells in  investigator-initiated clinical trials. We are seeking an experienced and motivated program manager who will be responsible for the execution of the program and who will closely work with the scientists, principal investigators and the hematologists involved in the project.

Question about this vacancy?
Carla Noom Carla Noom +31625210185 Recruitment Adviseur
About your role

Essential Duties And Job Functions
For a fast development of a newly developed CAR-T Cell Therapies. The project manager will:

  • Create and steer program teams, bringing together both the Amsterdam UMC team members and sourcing external subject matter experts where needed
  • Effectively manage the project timelines, deliverables, milestones and budget. Ensure that development plans are written and kept up to date. Take the responsibility of timely reporting of the project progress as well as planning/forecasting to sponsors, collaborators, stakeholders as well as to functional teams
  • Develop a robust and priority-based model to ensure rapid and effective tracking/monitoring and risk management, including any required action in the process of project.
  • Partner and oversee program teams to
    • generate a solid pre-clinical package
    • evaluate regulatory impact on programs
    • ensure manufacturing development, and validation leading up to GMP grade CAR T production
    • ensure facilities are in place to allow for GMP grade CAR T production
    • interact with CDMOs/CROs where needed
    • ensure timely execution of clinical trial(s) in collaboration with the clinical trial unit of the department of Hematology
    • monitor budget and resources
  • Collaborate with other functional departments (eg: laboratory, pharmacy, P&O, ) to resolve issues. Collaborate and negotiate with vendors in the supply or QC chain.
  • Partner with Medical Affairs, Government and Public Affairs, National and European regulatory agencies to ensure effective development and implementation of strategies, which are all are in compliance with national and European regulatory and legal requirements.
  • Develop effective working relationships with sponsors, collaborators and other key stakeholders.

About you

Knowledge, Experience and Skills

  • A university degree in Health Science
  • Demonstrated project/program management experience within the biotech/healthcare industry and ability to translate science into clinical practice. Ability to apply knowledge of drug/cell therapy development in an academic setting
  • Knowledge of GMP-compliant cell manufacturing processes, including regulatory requirements. Ability to determine priority actions that align with a fast and effective clinical implementation strategy of developed CAR-T cell therap(ies).
  • Knowledge of  viral vector-based CAR-T cell therapy product development and supply chain in hemato-oncology is a pre.
  • Knowledge of G(C)LP and GCP is a pre.
  • Analytical, strategical and pragmatical thinking, ability to identify and analyze complex issues, resilient profile with the ability to execute sound judgment and make decisions in ambiguous situations.
  • Excellent interpersonal and relationship building skills including communication and harmonization skills across teams as well as external parties.  Ability to resolve conflict and drive consensus among cross-functional teams within timelines.
  • Excellent and demonstrable skills of written and spoken English and Dutch and proficiency at communicating verbally and in written form.


  • Curious with learning agility
  • Operationally excellent
  • Organized with systematic approach to prioritization
  • Integrity and transparency
  • Teamwork
  • Striving for Excellence
  • Accountability
Our offer
  • A contract for one year (12 months) with the intention to extend for 24 months.
  • Besides a good basic salary, you will also receive an 8.3% year-end bonus and 8% holiday allowance. Calculate your net salary here.
  • Free and unlimited access to our online learning environment GoodHabitz.
  • Pension accrual with ABP, of which we pay 70% of the premium.
  • Reimbursement of 75% of your public transport costs. Would you rather travel by bike? Then we have a good bicycle scheme.
  • An active personnel association and the Young Amsterdam UMC association, both of which organise fun (sports) activities and event
About your workplace

The Department of Hematology of Amsterdam UMC is an (inter-)national leading academic Hematology Center, caring for patients with hematological diseases in the most innovative way. Hematologists are working closely together with scientists within the department in order to translate our own discoveries to the clinic. There is a long history with  investigator-initiated studies. You will work closely with the scientists, principal investigators and the hematologists involved in the project.

Amsterdam UMC has an open culture. This means that we hope that everyone feels welcome in our organization and that we strive to offer equal opportunities to everyone. We therefore cordially invite all interested parties to respond to this vacancy. Check out our approach to diversity and inclusion.
What to expect
A job in our beautiful capital city
Working for the favorite employer in healthcare (intermediary 2021)
All colleagues have the same goal: contributing to tomorrow’s care
There is room for development, deepening and broadening of your knowledge
An active staff association that organizes fun activities and arranges discounts on products and services for you
Amsterdam UMC innovates continuously, which requires a flexible attitude from everyone
Two large locations, good for your pedometer!
You have more than 15.000 colleagues, not all of whom you will get to know personally
Meet your colleagues Watch video’s of your future colleagues
Amsterdam UMC
Verpleegkundige visie
Let’s meet!

For further information about the position, please contact Lisette Bevaart, Program Manager Cell Therapy – LSMB, via 

For more information about the application procedure please contact Carla Noom, Recruitment Advisor, via 06-25210185

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. 

Acquisition in response to this vacancy is not appreciated.