Working at Amsterdam UMC

Postdoc researcher Vitiligo & Skin Cancer

Looking for a new challenge in cancer immunology research? This project offers an inspiring research opportunity in the field of skin cancer, autoimmunity and immunotherapy, in close collaboration with the clinic.
Postdoc researcher Vitiligo & Skin Cancer
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  • Hours: 30 36 uur per week
  • Division: Internal medicine
  • Contract type: fixed-term
  • Salary: € 2.911 - € 4.615
  • React until: 14 December 2021
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About your role

Understanding how the immune system interacts with cancer is crucial for effective cancer immunotherapy. Clinical and epidemiological data suggests a protective effect of vitiligo against non-melanoma skin cancer. In this project, you will explore this relation on multiple levels, in the field of cancer biology and immunology. You will investigate how vitiligo-based immune responses target basal cell carcinoma and squamous carcinoma.

You will pioneer on this topic and shape the project, based on your immunological knowledge and innovative ideas.  You will perform in vitro research using patient-derived immune and tumor cells, as well as in vivo experiments using relevant mouse models. To better understand therapy response and determine potential tumor antigens, you will acquire experience in advanced technologies, such as using Opal multiplex immunohistochemistry, Imaging Mass Cytometry (Hyperion) and RNAseq on tumor samples. In parallel, as part of an ongoing line of research in the lab, you will also investigate the synergy of monobenzone-imiquimod immunotherapy in vivo in a pre-clinical melanoma model. This is a new project that can lead to a new research line with consecutive funding potential.

Question about this vacancy?
Tanja Hart Tanja Hart +31621603178 Recruitment adviseur
The project

This research project is funded by a 3 year grant in collaboration with an industrial partner in the US, which provides the opportunity for you to interact with pharmaceutical industry during the project. This project contains a challenging new hypothesis with high impact research potential, to achieve new insights in skin cancer immunology. In addition, the project also harbours an extension of our ongoing research line on the development of vitiligo-inducing immuntherapy for melanoma. Depending on the results, you will be involved in the acquisition of consecutive funding to prolong the research line. This project thereby provides a new challenge for you to grow as independent researcher as well as optimal embedding in the research team.

About you

We are looking for a highly motivated and enthusiastic Postdoctoral Researcher (Postdoc) with a strong interest in immunology and oncology.

  • You have a University Master of Science (MSc) degree in a relevant study and a completed PhD, during which you received excellent scientific research training in the fields of immunology and oncology.
  • You are article 9 (FELASA) certified and have excellent practical skills and expertise in animal (mouse) work.(Current) experience with Imaging Mass cytometry and RNAseq is a plus, as well as a BROK certificate.
  • You have outstanding experimental research skills and academic skills, are well organized, goal-oriented and results-driven, and have a strong team spirit, but you can also function independently.
  • You have good communication skills in particular good written and spoken English scientific language skills .
Our offer
  • A jump start to your career in research work.
  • All te space for you to contribute shaping the care of tomorrow.
  • Working on large-scale and research project, with motivated colleagues from all over the world.
  • We offer a contract for a year (12 months) with the intention to extend for a term with a maximum of the project duration.
  • Additional benefits include an 8.3% end-of-year bonus and 8.0% holiday pay.
  • The base salary does not include holiday pay (8%) and a year-end bonus (8.3%). 
  • In addition to excellent accessibility by public transport, AMC also has a sufficient number of parking spaces for employees.
  • Pension is accrued at Be Frank. 
About your workplace

The Laboratory of Expermental Dermatology (LED) of the department of Dermatology is specialized in translational and immunological research on pigment cell disorders of the skin, including vitiligo and melanoma. You will work in the LED research team of approximately 10 colleagues, including research technicians, postdocs, PhD students and research staff members. The LED team closely collaborates with clinical staff members leading to fruitful interactions between lab and clinic. The LED is located at the department of Medical Biology, with state-of-the-art research facilities. The department of Dermatology of the Amsterdam UMC is the NFU acknowledged national center of expertise for pigment cell disorders, which creates an inspiring environment of clinical and scientific expertise for translational research. The department is part of the Cancer Center Amsterdam and the Amsterdam Institute for Infection and Immunity (AII) which both offer an excellent scientific and social environment in the field of cancer immunology.

What to expect
A job in our beautiful capital
Working for the most preferred employer in healthcare (intermediair 2021)
All colleagues have the same goal: contributing to tomorrow's care
We care not only for our patients, but also for you
Cooperation is characterised by mutual trust and interest in one another
We are constantly innovating, so you must be able to deal with change
Parking is limited at location VUmc, but by public transport you can get to the door
A full agenda, because our staff association organises many fun activities
Meet your colleagues Watch video’s of your future colleagues
Amsterdam UMC
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We look forward to receiving your motivation letter and CV within a list of publications.

Do you have any questions? For more information, please contact Prof. Dr. R.M. Luiten, via r.m.luiten@amsterdamumc.nl. 

For more information about the application process please contact Tanja Hart, Recruitment adviser, via 06-21603178.

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. If you join us, we ask for a VOG (Certificate of Good Conduct).