Working at Amsterdam UMC

Post-doctoral fellow "Off-the-shelf” CAR -engineered T cells

Are you a Post-doctoral fellow who likes the challenge to work with our specialist team on Off-the-shelf chimeric antigen receptor (CAR)-engineered T cells.? If you want to be part of this team apply now!
Post-doctoral fellow "Off-the-shelf” CAR -engineered T cells
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  • Hours: 36 uur per week
  • Location:
  • Contract type: fixed-term
  • Salary: € 2.986 - € 4.707
  • React until: 5 July 2022
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The project

The successful and promising clinical results of adoptive cell therapies with chimeric antigen receptor-engineered T cells (CAR-T cells) dictate for further advancements, which would enable their applicability for more patients and for more diseases. To attain broader relevance, our goal is to use iPSCs as a source of optimally effective and broadly applicable “off-the-shelf” CAR-T cells for the therapy of hematologic and other malignancies. Our ultimate goal is to implement our findings in GMP compatible manufacturing processes.

Question about this vacancy?
Tanja Hart Tanja Hart +31621603178 Recruitment adviseur
About your role

What will you do

As a post-doctoral fellow your main tasks will be:

-to use induce pluripotent stem cells (iPSC), molecular biology techniques and employ gene-editing methodologies to generate an unlimited source of CAR-T cells.

-to perform functional, transciptional and epigenetic data gathering, processing and analyses

-to collaborate with and supervise technicians and students

-to present the study and results at national and international scientific meetings

-to write scientific papers

About you

Your profile

We are looking for an enthusiastic, skilled, highly motivated and ambitious post-doctoral researcher who can work independently as well as in a team and is creative in seeking solutions to scientific questions showing capability for independent thinking. Since you will be working in an international environment you are expected to have excellent command of written and spoken English and able to effectively communicate scientific ideas.

As a postdoctoral fellow candidate you also have the following qualifications and experience:

- PhD degree in Immunology, Oncology or closely related biomedical sciences;

- expertise in molecular and cellular biology, gene editing and primary lymphocyte cultures;

- Candidates with expertise in iPSC/ESC cultures, CAR T cell development and animal (mouse) experimentation are encouraged to apply.

- Ability to work in a fast and result oriented manner.

- Good documentation and communication skills

- Writing and presentation skills

Our offer
  • A contract for one year (12 months) with the intention to extend for another 36 months.
  • Besides a good basic salary, you will also receive an 8.3% year-end bonus and 8% holiday allowance. Calculate your net salary here.
  • Free and unlimited access to our online learning environment GoodHabitz.
  • Pension accrual with ABP, of which we pay 70% of the premium.
  • Reimbursement of 75% of your public transport costs. Would you rather travel by bike? Then we have a good bicycle scheme.
  • An active personnel association and the Young Amsterdam UMC association, both of which organise fun (sports) activities and events.

For an overview of all our other terms of employment, see https://werkenbij.amsterdamumc.org/

About your workplace

The department of Hematology of the Amsterdam University Medical Centers-Location VUmc is one of the biggest Hematological Centers in the Netherlands. As part of the Cancer center Amsterdam (CCA), one of the five Amsterdam UMC research Institutes, the department is known for its high quality translational research aiming at the improvement of survival chances for patients with hematological malignancies.

You will be working in close collaboration with the Laboratory for Cell Therapy at Sanquin (dr M. Hansen and dr C. Voermans) for the GMP implementation. You will be working in a collaborative environment consisting of hematologists, experienced scientific staff, medical and non-medical researchers in training and experienced technicians.

Amsterdam UMC has an open culture. This means that we hope that everyone feels welcome in our organization and that we strive to offer equal opportunities to everyone. We therefore cordially invite all interested parties to respond to this vacancy. Check out our approach to diversity and inclusion.
What to expect
A job in our beautiful capital city
Working for the favorite employer in healthcare (intermediary 2021)
All colleagues have the same goal: contributing to tomorrow’s care
There is room for development, deepening and broadening of your knowledge
An active staff association that organizes fun activities and arranges discounts on products and services for you
Amsterdam UMC innovates continuously, which requires a flexible attitude from everyone
Two large locations, good for your pedometer!
You have more than 15.000 colleagues, not all of whom you will get to know personally
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Amsterdam UMC
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Let’s meet!

For more information about this position, you can contact Maria Themeli via m.themeli@amsterdamumc.nl.

For more information about the application procedure please contact Tanja Hart, Recruitment Adviser, via +31 6-21603178 or via t.hart@amsterdamumc.nl.

A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you. If you join us, we ask for a VOG (Certificate of Good Conduct). Foreign citizens need to provide comparable police clearing certificates.

Internal takes precedence over external in case of equal suitability.

Acquisition in response to this vacancy is not appreciated.