We are looking for two PhD candidates for the MARVY (Development of MRI-based endovascular procedures for Vascular Surgery) project in Amsterdam UMC, who will substantially improve magnetic resonance imaging (MRI) for the clinical evaluation and treatment of abdominal aortic aneurysms (AAAs). One PhD-student will be more focused on the clinical implementation (supervision Dr. Yeung, VUmc) and one will be focusing on advancing MRI techniques (supervision Prof. Nederveen, AMC). This job offer on VUmc is for the one PhD-student focusing on clinical implementation and development of MRI-based diagnosis and treatment of AAA. Currently there are several clinical challenges in the treatment of AAAs that require the development of imaging guidance in several stages of the disease, which are all radiation based. AAA progression can be monitored by advanced MRI methods; the procedure to place stents in the AAA can be performed in the MRI scanner requiring real time MRI and finally the success of stent placement can be monitored with MRI as well instead of with radiation based CT.
Your tasks will be:
In this project we will evaluate if diagnosis, treatment and follow-up of aortic aneurysms can be performed with advanced MRI methods. Together with the MR-Physics group we will develop quantitative MRI methods (e.g. flow and perfusion assessment) together with real time MRI for visualization of and localization of markers during an interventional procedure. To achieve this novel MRI postprocessing and reconstruction methods will be developed. Over the years the Applied MR Physics group of the Amsterdam UMC has pioneered in close collaboration with clinical partners the use of compressed sensing for accelerating quantitative imaging and currently several artificial intelligence (AI) based methods are under evaluation. Implementing these methods for MRI in AAAs requires a next step, as both the temporal and spatial resolution restraints are more severe than in current applications.
Our group has expertise in a large variety of advanced MRI methods and new endovascular therapies for aortic aneurysms, which will allow for the perfect environment to bring this project to a successful end. Furthermore, we work closely together with industrial partners enabling a rapid development and validation of the techniques.
We are searching for candidates who want to improve healthcare with a medical background . On the one hand, the student must enjoy to learn new technical approaches in MRI, perform data analysis and machine learning approaches that are informed by MRI physics. The candidate must function in a multidisciplinary team and collaborate with doctors to show the clinical advantages of the technique and get it implemented in the clinical workflow.
A candidate must have:
Additional skills (not obligated) we would like to see:
Working at the Amsterdam UMC means working in an inspiring and professional environment in which developing one`s talents and skills are encouraged. As PhD candidate, you have access to the Graduate School to further develop your skills. We offer a salary in line with the Collective Labor Agreement for University Medical Centers in the Netherlands (CAO UMC).
You will be part of the translational vascular research group and the MRI-physics group at the Amsterdam UMC (location AMC). Dr. Vincent Jongkind and Dr. Oliver Gurney-Champion and Dr. Pim van Ooij will be daily supervisors. Dr. Kak Khee Yeung and prof. Aart Nederveen will be the promotors. The translational vascular surgery research group and the MRI-physics research group offer a resourceful and stimulating scientific environment. We are an energetic and enthusiastic team of roughly 15 BSc/MSc students, 20 PhD candidates, 3 postdocs, 5 assistant professors and two professors. The MRI-physics group is part of the department of Radiology and Nuclear Medicine and the translational vascular surgery research group of the department of Surgery.
At the Amsterdam UMC, we see over 300 aortic aneurysms yearly and we are equipped with a hybrid endovascular room. We are also equipped with 10 state-of-the-art 1.5/3 Tesla MRI scanners and a 7 tesla MRI scanner. We have reserved MRI research hours on most scanners.
Preferred start date for this position is as soon as possible.
For more information about this position, you can contact Dr. Kak Khee Yeung via E: firstname.lastname@example.org or Dr. Vincent Jongkind (email@example.com)
For more information about the application procedure please contact Tanja Hart, Recruitment Adviser, via T: 06-21603178 or E: firstname.lastname@example.org
A reference check, screening and hiring test may be part of the procedure. Read hier whether this also applies to you.
Acquisition in response to this vacancy is not appreciated.